UMEM Educational Pearls

Category: Orthopedics

Title: Biceps rupture

Keywords: biceps, tendon, rupture (PubMed Search)

Posted: 12/24/2011 by Brian Corwell, MD
Click here to contact Brian Corwell, MD

The long head of the biceps originates from the glenoid tubercle and superior labrum. 

Rupture of the proximal biceps tendon comprises 90-97% of all biceps ruptures

Often in men aged 40-60y

     - Almost exclusively involves the long head.

     - Aka "Popeye Arm" (distal contraction of the muscle belly)

-          May be acutely traumatic or microtears & age associated degeneration

-          Minimal loss of function because short head of biceps remains attached

-          Many patients can be treated non operatively

-          Most asymptomatic after 4-6 weeks

-          Place in sling, ice, analgesia

-          Refer to ortho for re-evaluation and determination of operative versus conservative management

http://imaging.birjournals.org/content/15/4/193/F7.large.jpg



Category: Toxicology

Title: Hydrogen Peroxide

Keywords: hydrogen peroxide (PubMed Search)

Posted: 12/22/2011 by Fermin Barrueto, MD (Updated: 4/28/2024)
Click here to contact Fermin Barrueto, MD

Generally H2O2 is available OTC at a concentration of 3-9% and used as an antiseptic. Toxicity is by two methods: local irritation like a caustic and gas formation - both directly correlating with the % concentration. Some interesting findings have occurred with this ingestion including:

1) Portal vein gas seen on CT

2) Arterialization of O2 resulting in CVA

3) Encephalopathy with cortical visual impairment

4) MRI showing b/l hemispheric CVAs

Even use of 3% H2O2 for wound irrgation has caused subcutaneous emphysema and O2 emboli.

Treatment: XR/CT/MRI may detect gas, if present in RV should be placed in Tredelenburg and carefully aspirated through a central venous catheter. Anectdotal case reports have used HBO therapy when patients were critically ill.(1)

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Category: Neurology

Title: Management of Increased Intracranial Pressure

Keywords: increased intracranial pressure, opening pressure (PubMed Search)

Posted: 12/21/2011 by Aisha Liferidge, MD (Updated: 4/28/2024)
Click here to contact Aisha Liferidge, MD

  • When performing a lumbar puncture, an opening intracranial pressure (ICP) greater than 20 to 25 mm of H2O is elevated.  

 

  • If it is thought that a patient's headache is due to elevated pressure, cerebrospinal fluid (CSF) can be therapeutically removed.  It is typically recommended that the pressure not be lowered by more than 50% of the amount above which it is normal.

 

  • The source of elevated ICP should be determined and addressed.  Common causes of increased intracranial pressure include:

             --- Venous drainage obstruction (i.e. cerebral venous sinus thrombosis).

             --- Endocrine (i.e. obesity, hypothyroidism, Cushing's disease, Addison's disease).

             --- Medications (i.e. vitamin A, cyclosporine, lithium, lupron, oral contraceptives,

                  amiodorone, and antiobiotics such as tetracyclines and sulfonamides).

             --- Other conditions (i.e. pregnancy, steroid withdrawal, acromegaly, polycystic ovary

                  syndrome, systemic lupus erythematosus, sleep apnea, HIV).

         



Category: Critical Care

Title: Amiodarone-Induced Lung Toxicity

Keywords: amiodarone, lung toxicity, ARDS, infection, critical care (PubMed Search)

Posted: 12/20/2011 by Haney Mallemat, MD
Click here to contact Haney Mallemat, MD

Amiodarone-induced lung toxicity (ALT) is a serious and sometimes fatal complication of amiodarone use.

Symptoms range from mild (e.g., dyspnea with exertion) to acute respiratory distress syndrome and risk of death.

ALT is secondary to either release of toxic oxygen radials that are directly toxic to the lung or the reaction is secondary to an indirect immunologic reaction.

Risk factors for ALT: use > 2 months, dose > 400mg/day, advanced age, or pre-existing lung injury

ALT is typically a diagnosis of exclusion so suspect ALT through a detailed history; physical exam and radiology are non-specific. Lung biopsy is the only confirmatory test.

Treat ALT by discontinuing the drug, steroids, and supportive care. In rare cases where amiodarone cannot be safely discontinued (i.e., life-threatening arrhythmia), dosage should be reduced and steroids added immediately.

Generally, ALT is reversible with a good prognosis.

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Category: Cardiology

Title: rightward ECG axis

Keywords: ECG, EKG, electrocardiography, electrocardiogram, rightward, axis (PubMed Search)

Posted: 12/18/2011 by Amal Mattu, MD (Updated: 4/28/2024)
Click here to contact Amal Mattu, MD

There are a handful of conditions associated with a rightward axis on the ECG: left posterior fascicular block, ventricular ectopy, lateral MI (old), pulmonary hypertension (acute or chronic), right ventricular hypertrophy, hyperkalemia, misplaced leads, and toxicity of sodium channel blocking drugs, to name a few.

When you notice that the rightward axis is NEW compared to an old ECG, and there's nothing else on the ECG that's obviously diagnostic (e.g. hyperkalemia would also show peaked Ts; ventricular tachycardia would be wide complex and fast, etc.), in emergency medicine you should always think first and foremost of the following three possibilities:
1. acute pulmonary embolus
2. toxicity of a sodium channel blocking drug
3. misplaced leads

Pay attention to axis! Using the above rule can make rightward axis very simple and useful.

AM
 

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Category: Pediatrics

Title: Pediatric forearm fractures (submitted by Emilie Cobert, MD, MPH)

Keywords: Bayonet, fracture reduction technique, radius (PubMed Search)

Posted: 12/16/2011 by Mimi Lu, MD
Click here to contact Mimi Lu, MD

Pediatric forearm fractures:

- 75% occur at the distal forearm, often include both radius and ulna
- Risk factor for failure of closed management: increased initial fracture displacement
- Increasing use of operative management for these unstable fractures due to unsuccessful closed reduction
- Bayoneted fracture (two fracture fragments that lie next to each other rather than in end-to-end contact) often require pin repair.
- Attempt closed reduction in ED with such maneuvers as traction-countertraction, can be aided by finger traps.
- Other newer techniques include Lower Extremity-aided Fracture Reduction (LEAFR) maneuver (Eichinger, 2011) which utilizes the unaided single provider's lower extremity to place counter-traction on the arm while using dominant hand of provider for traction and the free second hand of provider to realign the deformity (place your flexed knee interlocked just proximal to patient's flexed elbow)
- Splint distal forearm fractures in pronation in long-arm cast.
 
Bottom line: The LEAFR is a newer clinically effective technique for reduction of bayoneted distal radius fractures in children for single providers resulting in decreased rates of operative management.
 
 
References:
Eichinger, JK, et al. A New Reduction Technique for Completely Displaced Forearm and Wrist Fractures in Children: A Biomechanical Assessment and 4-year Clinical Evaluation. J Pediatr Orthop. 2011 Oct-Nov;31(7):e73-9.


Category: Neurology

Title: Botulism

Keywords: botulism, descending paralysis, clostridium botulinum, weakness (PubMed Search)

Posted: 12/14/2011 by Aisha Liferidge, MD (Updated: 4/28/2024)
Click here to contact Aisha Liferidge, MD

  • While botulism is a rare condition (about 145 reported cases annually), it should still be considered in cases of descending neuromuscular weakness, as it can cause rapid loss of respiratory function and death (mortality < 8%).  Check patient's vital capacity.
  • Botulism results from ingesting (onset of symptoms 6 to 48 hours) or having contamination of a wound (onset 4-14 days; associated with intravenous drug use) with Clostridium botulinum, an anaerobic, spore-forming bacteria; it has been used as a bio-terrorist agent as well.
  • Patients typically present with anticholinergic symptoms and the four "D's" - (1) dry moth, (2) dysarthria, (3) diplopia, and (4) dysphagia.
  • The definitive diagnosis is made by isolating the toxin in serum and/or stool.
  • Treatment is supportive and might include use of equine trivalent anti-toxin and human botulism immunoglobulin.  Antibiotic and anti-cholinergic therapy has not been shown to be particularly effective.

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Category: Critical Care

Title: The Crashing Patient with PAH

Posted: 12/13/2011 by Mike Winters, MD (Updated: 4/28/2024)
Click here to contact Mike Winters, MD

The Crashing Patient with PAH

  • In recent weeks, we've highlighted some pearls regarding the management of patients with pulmonary arterial hypertension (PAH).
  • In the crashing patient with PAH, think about the following:
    • Catheter occlusion or malfunction (for those receiving IV prostacyclin analogues)
    • PE (for those inadequately anticoagulated)
    • Pneumonia
    • RV ischemia
    • GI bleeding
    • Ischemic bowel
  • In the patient receiving IV epoprostenol (Flolan) who presents with a catheter occlusion or malfunction, time is of the essence. Restart the medication through a peripheral IV as soon as possible.

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Category: Visual Diagnosis

Title: What's the Diagnosis?

Posted: 12/11/2011 by Haney Mallemat, MD (Emailed: 12/12/2011) (Updated: 8/28/2014)
Click here to contact Haney Mallemat, MD

Question

60 year old male with 6 months of weight loss and recent epistaxis. Diagnosis?

Show Answer



Category: Orthopedics

Title: Subtle radiographic signs of child abuse

Keywords: fractures, child abuse, radiology (PubMed Search)

Posted: 12/10/2011 by Brian Corwell, MD (Updated: 4/28/2024)
Click here to contact Brian Corwell, MD

Metaphyseal bucket handle and corner fractures are almost pathognomonic for child abuse

These injuries were originally identified by clinicians evaluating children with subdural hematomas

These injuries are typically seen in the ankles, knees, elbows and wrists

Violent twisting, shaking, or pulling across a joint creates shearing forces across the weak epiphyseal growth plate and metaphysis

This leads to

1)      A thin rim of mineralized metaphyseal bone aka  “bucket handle”  

http://rad.usuhs.mil/rad/home/peds/bucketarrow.jpg

OR

2)      Small flecks of bone from the metaphyseal corner adherent to periosteum

http://t2.gstatic.com/images?q=tbn:ANd9GcT0kZ3VR1f7MwRj7oIa6jaYVp_-f8kZ1NhSbw4kCTRGNLDJ1pKK9g



  • causes gastric outlet obstruction and vomiting
  • 1 in every 500 infants; with a 4:1 male-to-female ratio and a family history in another sibling
  • symptoms begin 2-4 weeks after birth, with projectile NON-bilious vomiting
  • firm, mobile, nontender, olive-shaped mass in right hypochondrium or epigastric area
  • diagnosis confirmed with US or upper GI series
  • treatment is a pyloromyotomy, but fluid and electrolyte replacement is vital in ED

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Category: Toxicology

Title: Warfarin management of ED patients

Keywords: warfarin, INR (PubMed Search)

Posted: 11/29/2011 by Bryan Hayes, PharmD (Emailed: 12/8/2011) (Updated: 12/8/2011)
Click here to contact Bryan Hayes, PharmD

A recent study highlighted the challenges we face managing ED patients on warfarin therapy. Some key observations about how we're doing: 

  • Only 71% of patients on warfarin had an INR checked
  • Nontherapeutic INRs were recorded for 49%; ED providers intervened to address these results in 21% of cases
  • 71% of patients with a supratherapeutic INR received an intervention compared with 9% of patients with a subtherapeutic INR
  • 30% of patients received or were prescribed potentially interacting medications
  • Recommendations for specific anticoagulation follow-up were documented for only 19% of all patients

Literature continues to show warfarin is the most dangerous medication for our patients. Meticulous monitoring and follow up will help us potentially avoid serious interactions and adverse events.

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Category: Neurology

Title: Micturation Syncope

Keywords: mictuation syncope, syncope, vagus nerve, vasovagal syncope (PubMed Search)

Posted: 12/7/2011 by Aisha Liferidge, MD
Click here to contact Aisha Liferidge, MD

  • Micturation syncope is a relatively rare phenomenon (2.4 to 8.4% of fainting episodes) which most commonly affects males, and can often be diagnosed by simply taking a thorough history.
  • Straining to urinate triggers the vagus nerve which results in hypotension and bradycardia; in turn, cardiac output and brain perfusion is decreased, often resulting in diaphoresis, pallor, and weakness, followed by syncope or fainting. 
  • This process is transient and vital signs as well as consciousness typically return to normal rapidly.
  • When evaluating a patient for syncope, pay close attention for the presence of the following factors in order to make the diagnosis:

             -- occurs during or immediately following urination, often when bladder is full.

             -- occurs at night or after standing from the recumbent position of a deep sleep to urinate.

             -- risk factors: enlarged prostate, alpha blocker therapy, dehydration, alcohol, fatigue.

  • Sometimes defecation, coughing, or severe vomiting can also result in syncope.

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Up until recently, a tight-fitting mask was one of the only ways to deliver non-invasive positive-pressure ventilation.

High-flow nasal cannulas (HFNC) have been adapted from use in neonates to adults to deliver continuous positive airway pressure (CPAP).

HFNC provides continuous, high-flow (up to 60 liters), and humidified-oxygen via nasal cannula providing positive pressure to the pharynx and hypopharynx. Patients tolerate it well and it is less claustrophobic than tight-fitting masks.

HFNC does not generate the same amount of pressure as CPAP so it may be best utilized as an intermediate step between low-flow oxygen (i.e., traditional nasal cannula) and non-invasive positive pressure ventilation with tight-fitting masks.

Check with your respiratory department if these devices are locally available.

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Minimizing interruptions in chest compressions during CPR is critically important. As an example of the adverse consequences of interruptions, consider the following finding from Edelson (Resuscitation 2010): for every 10 seconds of hands-off time during cardiac arrest, the patient's chances of successful return of spontaneous circulation decreases by 50% due to reductions in cerebral perfusion.

Next time you are involved in a code, keep this in mind, and do EVERYTHING POSSIBLE to minimize those interruptions in chest compressions.

 

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You just finished assessing a 6 month old in the Pediatric ED who can’t move his right leg.  You suspect child abuse.  You’re ready to order labs, a head CT, ophtho consult, skeletal survey and call Child Protective Services.   While your doing all of this, your medical student asks you, “What exactly are you looking for on the skeletal survey?”

A skeletal survey is mandatory for cases of suspected child abuse in children under the age of 2 years.  Approximately 60% of the fractures seen in abused children are younger than 18 months old.

When you are looking at a skeletal survey, carefully look for the following:

1. Multiple, healing fractures of various ages

2. Rib fractures, especially in the posterior ribs

3. Metaphyseal chip and buckle fractures

4. Spiral fractures in long bones (especially in children that can’t walk)

5. Skull fractures which are not simple and linear

6. Scapula fractures

 

More to come about child abuse…. 

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Category: Pharmacology & Therapeutics

Title: Emergency Hospitalizations for ADEs in Older Americans

Keywords: older adult, adverse drug event, ade, elderly, warfarin (PubMed Search)

Posted: 11/29/2011 by Bryan Hayes, PharmD (Emailed: 12/3/2011) (Updated: 12/3/2011)
Click here to contact Bryan Hayes, PharmD

A recent article estimated 100,000 emergency hospitalizations for adverse drug events in U.S. adults 65 years of age or older each year. Nearly half of these hospitalizations were among adults ≥80 years old and two-thirds were due to unintentional overdoses.

Four medications or medication classes were implicated alone or in combination in 67% of hospitalizations:

  • Warfarin (33.3%)
  • Insulins (13.9%)
  • Oral antiplatelet agents (13.3%)
  • Oral hypoglycemic agents (10.7%)

Opioids were #5. Digoxin was #7 and resulted in the highest percentage of hospitalizations per ED visit at 80%.

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Category: Toxicology

Title: High dose insulin in cardiogenic shock

Keywords: Insulin,beta blockers,calcium channel blockers (PubMed Search)

Posted: 12/1/2011 by Ellen Lemkin, MD, PharmD
Click here to contact Ellen Lemkin, MD, PharmD

High dose insulin is recommended in treatment of beta-blocker and calcium channel blocker overdose. In a recent observational case series of cardiogenic shock, high dose insulin was evaluated for efficacy and safety.

 
The overdoses were primarily calcium channel and beta blockers, but included other agents
like tricyclic antidepressants.
  • Insulin doses were given at a maximum of 10 units/kg/hour.
  • Seven patients who were on vasopressors when enrolled were tapered off when placed on high dose insulin.
  • 11/12 patients lived and were discharged from the hospital.
  • Adverse effects included hypoglycemia (19 events) and hypokalemia (8).
Bottom line: High dose insulin, when used in doses up to 10 units/kg/hr allows avoidance of vasopressors, and appears to be effective in the treatment of toxin induced shock in this small case series.

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  • Seizures occur commonly and it is estimated that 1 of 26 people will develop epilepsy at some point in their life.
  • A first seizure provoked by an acute brain insult is less likely to recur (3-10%) than a first-time unprovoked seizure (30-50% over the next 2 years).
  • As an emergency provider managing an adult who presents with their first-ever seizure, there are four primary questions that require answering:
  1. Was it in fact a true seizure? (often associated with tongue biting, urinary/bowel incontinence, preceding aura, post-ictal phase; examples of seizure mimics include syncope (i.e. cardiogenic, neurogenic, vasovagal), vertigo, myoclonic jerking, psychogenic convulsions, movement disorders.)
  2. Does the patient have epilepsy? (defined a having at least 2 unprovoked epileptic seizures by any immediately identifiable cause.)
  3. What type of epilepsy? (cryptogenic (i.e. of unknown etiology) or symptomatic (i.e. caused by prior central nervous system insult such as brain injury.)
  4. What is the cause? (metabolic panels to assess for uremia, electrolyte and glucose abnormalities, and drug intoxications should be performed, as well brain imaging to determine the presence of focal intracranial lesions.)
  • Many patients do not require anticonvulsant medication following a single, first time seizure; A general consensus is that such therapy should be strongly considered for initiation after a second episode of seizure activity. 

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Category: Critical Care

Title:

Posted: 11/29/2011 by Mike Winters, MD (Updated: 4/28/2024)
Click here to contact Mike Winters, MD

Hypotension in the PAH Patient

  • Hypotension in the critically ill patient with pulmonary arterial hypertension (PAH) must be rapidly treated to avoid cardiovascular collapse.
  • Hypotension in the PAH patient is not always due to hypovolemia.  In fact, excessive volume loading may further decrease LV stroke volume.  Consider starting with a fluid bolus of 250 ml of an isotonic crystalloid solution and monitoring response.
  • Patients with severe PAH may present to the ED with a continuous flow pump of a pulmonary vasodilator (epoprostenol, treprostinil).  These medications can also cause hypotension at excessive doses.  Consider decreasing the rate of the infusion by 25% to see if overdosing is the cause.

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